Glabellar Lines Treatment at KU64
[ Smooth away frown lines for a relaxed and youthful appearance ]
Glabellar lines – also known as frown lines – are the vertical wrinkles that form between the eyebrows. They often appear when we frown or concentrate, but over time, they can become permanent even when the face is at rest. At KU64, we offer gentle and effective treatments to reduce these expression lines and restore a relaxed, youthful facial expression.
From Glabellar Lines to Crow’s Feet: Why Do Wrinkles Form?
Every wrinkle tells a story—of laughter, deep thought, sunny days, or moments of stress. At some point, we notice that these lines remain even when our face is relaxed and deepen over time. While some people see the first signs of wrinkles in their twenties, others maintain firm, youthful skin well into their forties. But why is that? Let’s take a look at the causes.
Facial expressions, stress, and natural aging
Every time we laugh or squint, our facial muscles contract. Over the years, these micro-movements leave marks on the skin. The forehead is particularly affected, as we tend to use these muscles frequently. Alongside horizontal forehead lines, the glabellar lines are often among the first to appear visibly.
As we age, the skin’s production of collagen and elastin—proteins responsible for firmness and elasticity—slows down. As these components break down, the skin can no longer fully smooth out after facial movements. Fine lines that initially appeared only with certain expressions eventually become permanent.
Stress can accelerate this process. Those under constant tension often furrow their brows or frown—a habit that deepens glabellar lines over time. In addition, stress hormones like cortisol further reduce collagen and elastin and impair the skin’s regenerative ability.
Genetics and environmental influences
Alongside facial expressions and the natural aging process, genetics also play a major role in wrinkle formation. Some people naturally have thicker, more resilient skin that resists deep lines for longer. Others have a finer, more delicate skin structure that shows signs of aging earlier. A genetic predisposition to lower collagen production can also lead to earlier wrinkling—even with excellent skincare and a healthy lifestyle.
But it’s not just genes—external factors also significantly influence how quickly wrinkles develop. One of the leading causes of premature aging is UV exposure. It accelerates the breakdown of collagen and elastin, causing the skin to lose firmness. UV rays also damage both the skin barrier and deeper layers, impairing the skin’s ability to regenerate. So the best tip for slowing skin aging? Use sunscreen daily!
Other factors such as pollution, lack of sleep, and poor nutrition can also rob the skin of its glow. Free radicals from exhaust fumes and environmental toxins attack skin cells and speed up aging.
So while many factors contribute to wrinkle formation, the good news is that many of them are within your control. And there’s even better news: Thanks to modern aesthetic treatments like targeted botulinum toxin applications, wrinkles can be significantly reduced.
Remove Glabellar Lines & More Wrinkle Treatments at KU64 Berlin
Not a fan of that stern or tired look in the mirror that doesn’t match how you actually feel? If you’d like to smooth your forehead or other facial areas without undergoing plastic surgery or a forehead lift, aesthetic medicine offers a range of non-invasive and minimally invasive options.
Botulinum toxin – the most effective solution for a smooth forehead
When it comes to treating forehead wrinkles—especially glabellar lines—botulinum toxin (Botox) is often the treatment of choice. It relaxes the muscles responsible for wrinkle formation, allowing the skin to smooth out while also preventing further lines from developing. The key advantage: with the right dosage, your natural facial expressions are preserved. Only the constant unconscious muscle tension that causes the wrinkles is reduced.
The effects of botulinum toxin begin within the first few days after treatment and are fully visible within a week. Soon, your forehead appears more relaxed, your glabellar lines are visibly reduced, and your overall expression looks softer and more refreshed. As the body breaks down the substance slowly, results typically last three to six months. After that, the treatment can easily be repeated.
Another advantage of minimally invasive wrinkle treatments like botulinum toxin injections: unlike plastic surgery, there’s no extended recovery or downtime. After a short period of rest, you can return to your daily routine right away.
Other Treatments for Forehead Wrinkles: Hyaluronic Acid, Laser & More – A Comparison
Looking for plumping rather than muscle relaxation? Hyaluronic acid may be a great alternative. This naturally occurring substance binds moisture and adds volume under the skin. For deep-set wrinkles, a combination of botulinum toxin and hyaluronic acid often delivers the best results.
Modern laser treatments are another option to reduce wrinkles. They stimulate natural collagen production and enhance the skin’s texture in the long term. However, several sessions are usually required for visible results.
If you’re seeking a long-term solution, plastic surgery might be the answer. However, procedures like a forehead lift involve more effort, higher risks, and longer recovery periods. That’s why it’s essential to receive thorough consultation and guidance from your medical professional.
Ultimately, the best treatment for wrinkles depends on the results you’re looking for and how much time and budget you’re willing to invest in treatment and recovery. During a personal consultation, we’ll help you find the solution that fits your needs best.
Why Botulinum Toxin Is So Popular for Treating Glabellar Lines
Botulinum toxin is a go-to for both doctors and patients when it comes to wrinkle treatment—especially for removing glabellar lines. It’s an effective and well-established solution for treating forehead lines and frown lines alike.
How does botulinum toxin work?
Glabellar lines and horizontal forehead wrinkles are primarily caused by overactive muscles in the forehead or between the eyebrows. Repeated frowning—whether due to stress, concentration, or habit—causes the skin to fold in the same spots again and again. Over time, these lines remain visible even when the face is at rest.
This is exactly where botulinum toxin comes in: it blocks the communication between nerves and muscles in a targeted way. The treated muscles relax, and the overlying skin smooths out. That makes it a highly effective treatment for reducing or even removing glabellar lines.
The Treatment – Quick, Precise, and Gentle
A wrinkle treatment with botulinum toxin usually takes just 15 to 20 minutes. After analyzing your facial muscles, the substance is injected into the targeted areas using a fine needle.
At KU64 Berlin, we place great importance on precise dosing and application. That’s how our doctors achieve natural-looking results: your forehead won’t look stiff—it’ll appear relaxed and visibly smoother.
Results: When will I see an effect, and how long does it last?
Changes become visible within three to four days after treatment. About a week after your botulinum toxin injection, the full effect sets in: your glabellar lines appear smoothed, and your overall facial expression looks softer and more relaxed.
Depending on individual factors like metabolism, skin type, and lifestyle, the results of a botulinum toxin treatment usually last between three and six months. With regular touch-ups, the effect can be maintained long-term—preventing deep wrinkles from reappearing.
Total relaxation: More aesthetic treatments with botulinum toxin
Treating glabellar lines is one of the most common uses for botulinum toxin—but by far not the only one. Whether forehead wrinkles, crow’s feet, or downturned corners of the mouth, many signs of skin aging can be gently corrected with botulinum toxin—without compromising your natural facial expressions. Fine lines can be reduced, facial features harmonized, and even certain muscle tensions targeted.
Gentle smoothing of forehead lines and crow’s feet
It’s not just glabellar lines—your entire forehead is one of the most expressive areas of the face. Whether you’re raising your eyebrows or concentrating deeply, this area is under constant strain. Over time, this leads to horizontal lines across the forehead: the classic forehead wrinkles.
Our facial expressions also cause so-called crow’s feet—the fine lines at the outer corners of the eyes. These become especially visible when smiling or squinting and tend to deepen with age.
Botulinum toxin specifically relaxes the muscles in these areas, allowing the skin above to smooth out. The result: your forehead appears more rested, the eye area looks fresher, and your entire face gains a relaxed, youthful appearance.
Softening lip lines and lifting corners of the mouth—for a radiant smile
Fine lines around the lips tend to develop in people with expressive facial movements and naturally thinner skin. Smokers are especially prone to vertical lines above the upper lip—commonly known as smoker’s lines.
As we age, the corners of the mouth may also begin to turn slightly downward. Many of our patients feel this makes them appear grumpy or unhappy—even when they’re not.
With precise botulinum toxin injections, these lines around the mouth and lips can be softened, and the corners of the mouth gently lifted. The result is a more positive, open smile—without compromising your natural expression.
Gummy smile, masseter & more—botulinum toxin for a balanced facial profile
In addition to wrinkle-smoothing treatments, botulinum toxin has several lesser-known yet highly effective aesthetic applications. One of these is correcting a gummy smile—where too much gum is visible when smiling. By gently relaxing specific muscles, the balance between lips and teeth can be harmonized for a more attractive smile.
Botulinum toxin can also be used to subtly reshape the face. For those bothered by a prominent jaw muscle (masseter), targeted injections can relax the area, resulting in a slimmer and softer lower face—ideal for anyone seeking a more contoured jawline.
This makes botulinum toxin a highly versatile treatment. Whether you’re aiming for more refined facial features, a fresher appearance, or more harmonious proportions, botulinum toxin offers a gentle but effective alternative to plastic surgery. Our specialists are happy to advise you on which treatment is best suited to achieve your desired result.
Safety and Tolerability of Botulinum Toxin
If you’re considering an aesthetic treatment with botulinum toxin, you’re likely wondering about its safety. After all, it’s a substance that specifically relaxes muscles—an intervention in your body’s natural function.
As with any medical treatment, there’s a potential for side effects. The good news: botulinum toxin has been used for decades in both aesthetic and medical treatments and is considered one of the safest and best-tolerated methods for wrinkle reduction—when administered professionally and in appropriate doses.
Side effects and risks of botulinum toxin
Botulinum toxin is injected in minimal amounts and remains active only in the treated area. Severe side effects are extremely rare. However, as with any injection, temporary reactions may occur—such as slight redness, swelling, or small bruises at the injection site. These typically disappear within a few days.
In rare cases, there may be temporary weakening of nearby muscles. This can cause slight drooping of the eyebrows or an asymmetrical appearance. Such effects are not permanent, as the body breaks down the substance completely within a few months.
To ensure the best results, it’s important to follow certain aftercare guidelines: avoid intense physical activity, direct sun exposure, and sauna visits for a few days after treatment. This allows the substance to distribute properly and unfold its full effect in the muscles.
At KU64 in Berlin, our experienced doctors will inform you in detail about all possible risks and answer any questions you may have. Feel free to contact us for an initial consultation!
Is Botulinum Toxin Right for Me?
In general, botulinum toxin is suitable for most people who want to reduce wrinkles gently or refine certain facial features. However, treatment is not recommended in certain cases. We advise against it if you:
are pregnant or breastfeeding
have a neuromuscular disorder affecting muscle activity
are allergic to any ingredient in the injection
If none of these apply to you, botulinum toxin is a safe and well-tolerated method when administered by a trained professional—to smooth wrinkles and relax your facial expression.
Still Have Questions? Here's How to Reach Us
Our team of dental and aesthetic specialists is happy to answer any questions and provide further information about our wrinkle treatment options. Schedule your appointment by phone at 030-8647320 or conveniently online via our appointment calendar—or email us at info@ku64.de. We’ll get back to you promptly! Our practice team is here for you seven days a week.
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Our practice in the heart of Berlin-Charlottenburg is just a short walk from the Adenauer Platz U-Bahn station. Patients arriving by car can use our free parking spaces in the courtyard.
Frequently Asked Questions About Botulinum Toxin
Can glabellar lines disappear completely?
With the right treatment, glabellar lines can be significantly reduced. Whether they can be fully smoothed out depends on how deep they already are. Early treatment with botulinum toxin relaxes the muscles between the eyebrows, allowing the skin to smooth out and helping to prevent further wrinkle formation. In cases of deeper glabellar lines, a combination with hyaluronic acid may be recommended to plump up the skin and make the line less visible. Regular treatments can help prevent the lines from reappearing over time.
How much does botulinum toxin treatment cost?
Costs depend on the treatment area, amount of product used, and individual factors like muscle activity. For smaller areas such as glabellar lines, prices typically range from €150 to €350. Larger treatments involving multiple areas or the entire forehead can cost up to €600. At KU64 in Berlin, you’ll receive a transparent and personalized quote during your consultation.
How long does Botox last in glabellar lines?
The effects of botulinum toxin in the glabellar area usually last three to six months, depending on your muscle activity, metabolism, and lifestyle. Once the effect wears off and the lines begin to return, the treatment can be repeated. With regular use, the results may even last longer, as the treated muscles adapt to their relaxed state.
What is the difference between hyaluronic acid and botulinum toxin?
The effects of botulinum toxin on glabellar lines typically last between three and six months, depending on individual factors such as muscle activity, metabolism, and lifestyle. As the effect gradually fades and the lines begin to reappear, the treatment can be easily repeated. With regular sessions, the results often last longer over time, as the treated muscles become accustomed to a more relaxed state.